Vitamin C Retard 40 tablets YAMAMOTO
Vitamin C Retard is a high-dose vitamin C dietary supplement in slow-release coated tablets. Vitamin C contributes to the normal function of the immune system and the protection of cells from oxidative stress.
With winter approaching, the race to protect oneself from colds, seasonal ailments, or the flu begins. Vitamin C is usually the most popular and trusted folk remedy, and it's often the first choice. However, relegating it to the sole role of supporting these ailments would be far from reductive, as vitamin C is a true multitasker, participating in numerous metabolic processes as well as playing an important role in strengthening the immune system.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin, like B vitamins and folic acid. This means it can only be stored in the body in limited amounts and must be ingested daily through food, requiring a continuous supply since the human body is unable to synthesize it.
Vitamin C is found in large quantities, especially in fresh vegetables and citrus fruits. Among the foods that contain it most are kiwis, which provide 93 milligrams of the vitamin per 100 grams; papaya (which provides 60 milligrams); oranges (with 59 milligrams!); strawberries (58 milligrams); lemons (53 milligrams); and pineapple (47.8 milligrams), to name just a few famous sources.
Unfortunately, in modern times, we often have to consider whether or not to supplement with vitamin C, especially during certain periods or situations of increased need. It's important to emphasize that today we must recognize that our diet is lacking in wholesome, fresh fruits and vegetables: the food supply chain is long, and often foods appear fresh to our tables but have actually been preserved for days with special treatments. It's important to understand that vitamin C is lost significantly depending on the time between harvesting and consumption, and its preservation significantly reduces its content. In fact, the fresher and less cooked the food, the greater the amount of the vitamin. It's an extremely labile vitamin, and being highly soluble in water, it quickly oxidizes in an aqueous solution in the presence of metals, alkalis, light, and oxygen. Cooking in water, of course, drastically alters its concentration in foods. In addition to their preservation, the chemical treatments to which the various foods we eat have a negative impact, depleting the content of precious micronutrients. Therefore, even many fruits and vegetables we eat contain minimal or no vitamin C at all. It's therefore undeniable that our diet often fails to meet our daily requirements, especially at certain times of the year. Besides a diet low in fruits and vegetables, various factors, especially lifestyle factors, contribute to the deficiency: smoking, pollution, stress, cold, imbalances in minerals such as copper and iron, and even certain therapies that can cause the body to lack sufficient vitamin C.
The common belief that it's such an important vitamin is more than deserved: this vitamin is essential and performs numerous important functions in the body. It was first studied in 1747, when researchers discovered that vitamin C helped protect malnourished sailors from scurvy (a vitamin C deficiency disease). As research continued, its use and medical and scientific support continued to expand enormously.
Among vitamins, no other vitamin plays as many roles as vitamin C, and its antioxidant action, which protects the body from free radicals, is particularly important. Excess free radicals can cause oxidative stress, which is associated with or correlated with the onset of various diseases and accelerates the aging process.
But the effects of vitamin C are truly multifaceted: it strengthens the function of phagocytes, increases antibody production, stimulates interferon synthesis and carnitine biosynthesis, has an anticholesterol effect, and, as already mentioned, destroys oxygenated free radicals, hydroxyl radicals, superoxide radicals, and oxygen radicals. It participates in cellular respiration processes and plays a role in the development of fibroblasts. A very important function, increasingly prominent for various joint problems or in aesthetic medicine, is its involvement in the synthesis of collagen, a protein necessary for the formation of connective tissue in the skin, ligaments, and bones. The lubricating fluid of the joints, called synovial fluid, becomes more fluid when serum ascorbic acid levels are high, promoting greater autonomy of movement.
Vitamin C plays an important role in the healing of wounds and burns because it facilitates the formation of connective tissue in scars. It supports physical stress, as it also plays a role in the formation of adrenal hormones, and its role in supporting iron absorption is well known. Its protective role extends not only against free radicals, but also counteracts the toxic effects of nicotine, benzoate, nitrogenous compounds, cytotoxics, and ionizing radiation.
Under conditions of "stress", it is consumed even more rapidly by the body, and it is necessary to talk about its "absorption" problems, often very little known or given little consideration by the "ruthless" marketing world of many companies.
Blood ascorbic acid levels peak two to three hours after ingestion, then decline as elimination begins through urine and sweating. Most vitamin C is eliminated from the body within a few hours, which is why it should be taken several times a day. But be careful: increased urinary elimination due to increased vitamin C intake does not mean that body tissues are saturated. The fact remains that the human body needs it, and increasingly so as we age.
When taken orally, most of the vitamin is absorbed through the mucous membranes of the mouth, stomach, and upper small intestine. The higher the dose, the lower the percentage absorbed. Sounds strange, right? A dose of less than 250 mg can be almost completely absorbed (about 80 percent), while a dose greater than 2 grams will absorb 50%. Since a healthy body can only absorb a certain amount over a certain period of time, taking large doses of vitamin C at a time, if not needed, causes increased elimination of unmetabolized ascorbic acid. (Note: In therapeutic treatments, intravenous injections of a few grams of ascorbic acid are much more effective than oral administration of the same amount, but that's another matter.) Therefore, it's virtually useless to "overdose" megadoses of oral vitamin C in a single dose, as this would only serve to "enrich" the urinary vitamin C content or cause potential overdose problems. Malabsorption from a vitamin C overdose can cause gastrointestinal problems, such as diarrhea, or even heartburn or reflux. At the kidney level, especially in those most predisposed, an excess of plasma ascorbic acid can also lead to the formation of kidney stones, due to the increased production of oxalic acid (during the catabolism phases of vitamin C) and therefore oxalates.
To address these potential reasons for poor vitamin C supplementation, the new Vitamin C Retard that we have added to the Yamamoto® Research catalog is a very convenient and effective solution. Its "delayed" tablet formulation makes vitamin C absorption more effective in the intestine, allowing for a gradual release of its contents and a longer-lasting bioavailability of this precious vitamin for its various defensive, protective, anti-aging functions, and more. This prevents problems of malabsorption of the active ingredient or excessively increasing ascorbic acid levels in the blood, thus avoiding the risk of expelling excessive amounts of vitamin C in the urine.
| Nutritional information | Per daily dose (2 tablets) |
| Vitamin C | 1000 mg (1250% RI*) |
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*AR: reference assumptions |
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Vitamin C (L-ascorbic acid), bulking agents: calcium phosphate, microcrystalline cellulose; stabilizers: hydroxypropyl methylcellulose, mono- and diglycerides of fatty acids, cross-linked sodium carboxymethylcellulose; glazing agents: polyvinyl alcohol, polyethylene glycol, talc; anti-caking agents: magnesium salts of fatty acids, silicon dioxide.
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